Connery's suave and charismatic portrayal of the fictional British secret agent James Bond in the early Bond films, such as "Dr. No," "Goldfinger," and "From Russia with Love," solidified him as the definitive 007
Ford's adventurous and rugged portrayal of the archaeologist and adventurer Indiana Jones in the "Indiana Jones" film series, including "Raiders of the Lost Ark," "Indiana Jones and the Temple of Doom,"
Nimoy's logical and stoic portrayal of the half-human, half-Vulcan science officer Spock in the "Star Trek" franchise, spanning from the original series to numerous films, has left an indelible mark on pop culture
Hamill's portrayal of the idealistic young Jedi Knight Luke Skywalker in the original "Star Wars" trilogy, including "Star Wars: Episode IV - A New Hope," "Star Wars: Episode V - The Empire Strikes Back,"
Reeve's portrayal of the Man of Steel in "Superman: The Movie" and its sequels, including "Superman II" and "Superman III," defined the role for generations to come, embodying the iconic superhero's strength, nobility, and sense of justice.
Downey Jr.'s charismatic and witty portrayal of billionaire inventor Tony Stark, aka Iron Man, in the Marvel Cinematic Universe, including the "Iron Man" trilogy and "The Avengers" films
Depp's eccentric and swashbuckling portrayal of the pirate Captain Jack Sparrow in the "Pirates of the Caribbean" film series, including "Pirates of the Caribbean: The Curse of the Black Pearl," "Dead Man's Chest,"
Hopkins' chilling and unforgettable portrayal of the brilliant but psychotic cannibalistic serial killer Hannibal Lecter in "The Silence of the Lambs," for which he won an Academy Award
Hanks' endearing and heartwarming portrayal of the titular character in "Forrest Gump," for which he won an Academy Award for Best Actor, has made him forever associated with the lovable and simple-minded yet wise